The star reduction, like many other aspects in photography, is something very subjective, since there are people who like images with many stars and others who prefer them with very few. Precisely because of this, in Nebulb you can apply the star reduction gradually (so each user can set the level of reduction that he/she likes the most for each photography).
That said, one thing that is usually taken into account when applying star reduction is that there are very characteristic stars that, in the case of not appearing in the image (or being very dimmed), can generate a somewhat strange sensation in the observer.
An example of this are some of the stars in the galactic centre of the Milky Way, such as those in the Lagoon nebula or in the Antares region.